The main speaker for the ceremony is Alabama Attorney General Luther Strange.
Last year's vigil drew more than 550 people to view the unveiling of a fountain honoring local victims.
Walker County District Attorney Bill Adair, whose office sponsors and organizes the event, said the ceremony was important so the community never forgets those victims and so the survivors know they aren't alone.
The vigil is scheduled to coincide with National Crime Victims' Rights Week, which is April 8-12.
Other speakers will include Adair, state Sen. Greg Reed, local ministers and victim representatives.
There will also be a video presentation honoring the victims and special music.
In the event if inclement weather, the event will be held at the Community Health Systems Activities Center. Lawn chairs are recommended for the event due to the limited seating available.