The Bulldogs (24-8) take on Handley (19-7) at noon today at Alabama State's Acadome in Montgomery.
Carbon Hill brings an 11-game winning streak into the game. The Bulldogs earned a spot at the regional with a win over Bibb County last week.
The Tigers are also on a hot streak, winning 13 of their last 15 games. Handley is in the state's Sweet 16 one year after finishing 9-16.
Carbon Hill girls basketball coach Wade Tittle has four key players — Caroline Dodd, Savanna Lawson, Molli Clark and Abby Tittle — back from last year's team that lost to Childersburg 49-33 in its regional opener. Carbon Hill held a halftime lead in that game, but was held to just nine points in the second half.
The Bulldogs are hoping for a better outcome today.
"We are going to have to do two things — rebound the ball and shoot it well." Tittle said. "We rely on shooting the 3 and that's gonna be important. We've got to make our share of them and we need to get some baskets in transition. They are a really good half-court, man-to-man team so what we do in transition will be huge.
"On the defensive end, we've got to protect the paint and limit them to one shot. Rebounding will be the major factor in the game. From a mental standpoint, I'm sure we will have some nerves, but we got four girls who played in this game last season, so I expect us to put that aside and go play ball."